Embryonic development

After successful fertilization, an embryo develops from the egg cell. The development of the embryo in the following hours and days is decisive for the success of the infertility treatment.


We refer to a poor embryonal development when the embryos separate too slowly or even remain motionless in the days after fertilization. In addition, the quality of the embryos in the laboratory can be judged by a scoring technique and predicted by using various nidation probability parameters.

  • High level of limited sperm quality (eg cryptozoospermia or via testicular biopsy collected sperm cells)
  • Reduced oocyte quality (eg higher maternal age, hormone imbalances, poor reaction to stimulation, overweight)
  • Genetic embryo disturbance
  • Infection
  • Complete hormone status with a thyroid stress test (TRH-test)
  • Spermiogram examination with ejaculation bacteriology and extended diagnostics (eg hyaluronan binding, genetic examination of the sperm cells)
  • Chromosome examination of the couple (cytogenetic)
  • Treatment of possible infections
  • Sperm extraction directly from the testicles (testicular biopsy – TESE)
  • Thyroid treatment
  • Pre-implantation diagnostic of the embryo
  • Egg cell donation
  • Specific fertilization techniques
  • In-vitro maturation (IVM) – maturation of the follicle in a test tube
  • Embryonic culture in the time-lapse incubator