The Intracytoplasmatic sperm injection (ICSI)

In many cases, there are too few sperm cells available which are motile and of normal morphology. In such cases, it is likely that no egg cell can be fertilized when the sperm cells are added.

For such cases, the intercytoplasmic sperm infection (ICSI) technique is recommended. This means that even with a poor sperm test result fertilization can be achieved. The minimum requirement is one motile sperm cell per egg cell.

IMPORTANT: even if the ICSI technique is used, fertilization can fail to take place or only a few of the egg cells can be fertilized. As with traditional IVF (in-vitro fertilization) this can be due to the egg cells or the sperm cells. Unfortunately, we mostly cannot give an exact reason as this is not possible with today’s methods.

The ICSI technique has been used for more than 20 years and is an established and safe treatment method.

However, it is to be considered that using this method sperm cells with a possible genetic modification might be used for fertilization. Sperm from men with a highly limited sperm count (<1 million sperm/ml or mostly immotile or morphologically changed sperm cells) show chromosomal changes more frequently even if the men themselves do not suffer from chromosomal anomalies. In such cases we recommend using the current methods of prenatal diagnostics should a pregnancy be achieved.