The preimplantation diagnosis (PID) can be considered an earlier form of pre-natal diagnostics. Cell biological and molecular genetic assays are used to decide whether or not an embryo should be implanted into the uterus. In order to perform a pre-implantation diagnosis, an in vitro fertilisation procedure is necessary.
The biopsy of polar bodies of the egg cell is an exceptional variant of the preimplantation diagnosis. The polar body diagnosis is an examination method used for indirect genetic analysis of the egg cells, and is not subject to the regulatory guidelines of the Austrian law on reproduction. If this less invasive examination method is not sufficient to induce pregnancy, or to avoid a miscarriage or stillbirth, in medically indicated cases the Austrian law on reproduction allows for preimplantation diagnosis and therefore a direct examination of the embryo can be performed.
The following explanations are intended to clarify the difference and applications of the two techniques. Both treatments are available at the Kinderwunschzentrum under consideration of the legal framework.